Home-cage ethanol consumption and motor activity: lack of relation to either initial activity or amphetamine-induced...

In two separate studies, the relationship between home-cage, two bottle ethanol/water consumption and both initial motor reactivity to a novel environment and amphetamine induced motor activity was determined in nonselected Wistar rats. In neither study was any correlation found. While home-cage ethanol consumption may not be an accurate measure of ethanol self-administration, the studies suggest that unlike reports for other drugs of abuse, there does not appear to be a simple relationship between alcohol preference and motor activity.