[Determination of multiple forms of leucine aminopeptidase in blood plasma]

The methods of evaluation of different forms of leucine aminopeptidase (LAP) activity in human serum were elaborated. It was shown, that there are some forms of LAP in serum which has different pH optimum and different sensitivity to L-methionine and other substrates. It was found, that these forms of LAP have different activity in the blood serum of adults and infants. The conclusion was drawn about diagnostic value of LAP forms in the infants with periventricular brain damages.