Histocompatibility leukocyte antigens in Rokitansky-Küster-Hauser syndrome

Histocompatibility leukocyte antigens of 32 patients with Rokitansky-Küster-Hauser syndrome were compared with a control healthy population of 100. For analysis chi 2 with Yates' correction and Bonferroni criterion for multiple comparisons were used. Seven antigens were significant in the chi 2 test, but only three were confirmed in the Bonferroni criterion (Aw19, DRw52, and DQw1) (p < 0.001). The study showed certain associations between Rokitansky-Küster-Hauser syndrome and the major histocompatibility complex.