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["Bronze baby" syndrome]

S Rodot1, J P Lacour, C Dageville

  • 1Service de Dermatologie, Hôpital Pasteur, Nice.

Annales De Dermatologie Et De Venereologie
|January 1, 1994
PubMed
Summary

Bronze baby syndrome is a rare complication of phototherapy for neonatal jaundice. This condition, caused by cholestasis, leads to a grey-brown skin discoloration in infants, which resolves after treatment.

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Area of Science:

  • Neonatology
  • Pediatric Gastroenterology
  • Dermatology

Background:

  • Neonatal jaundice is common, often treated with phototherapy.
  • Bronze baby syndrome is a rare, adverse reaction to phototherapy.
  • It is associated with impaired liver function, specifically cholestasis.

Observation:

  • A premature infant developed a grey-brown skin discoloration during phototherapy for hemolytic jaundice.
  • The infant had Rhesus incompatibility and cholestasis due to thick bile.
  • This coloration is linked to the accumulation of unexcreted photoproducts.

Findings:

  • The premature infant's bronze coloration was attributed to cholestasis and phototherapy.
  • Abnormal photoproduct accumulation caused the skin discoloration.
  • The condition resolved spontaneously after phototherapy cessation.

Implications:

  • Identifying the underlying liver disease is crucial for prognosis.
  • Bronze baby syndrome highlights the importance of monitoring liver function during phototherapy.
  • This case underscores the need for further research into phototherapy complications.

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