Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[A new method for measuring internal ear circulation using colored microspheres]

M Suckfüll1, S Holtmann, R Hecht

  • 1Klinik für Hals-, Nasen- und Ohrenkranke, Ludwig-Maximilians-Universitäts München.

Laryngo- Rhino- Otologie
|March 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Recurrent serious posttonsillectomy hemorrhage].

Laryngo- rhino- otologie·2010
Same author

[Rheopheresis as a successful second-line treatment for sudden hearing loss].

HNO·2010
Same author

STUDIES IN SENSITIZATION TO SKIN : I. THE PRODUCTION OF ANTIBODIES TO SKIN BY MEANS OF THE SYNERGISTIC ACTION OF HOMOLOGOUS SKIN ANTIGEN AND STAPHYLOCOCCUS TOXIN.

The Journal of experimental medicine·2009
Same author

[An unusual case of carotid arrosion bleeding].

HNO·2009
Same author

Detection of HIV-1 in alternative specimen types using the APTIMA HIV-1 RNA Qualitative Assay.

Journal of virological methods·2009
Same author

WITHDRAWN: [Effects of atorvastatin on presbyacusis and tinnitus : A prospective, randomized, double-blind clinical trial.]

HNO·2007
Same journal

Guideline-Based Cochlear Implant Care: A Model for Structuring Delegated Technical Aftercare.

Laryngo- rhino- otologie·2026
Same journal

Audiometric evaluation and quality-of-life in OSIA users - a retrospective monocentric study.

Laryngo- rhino- otologie·2026
Same journal

[Diagnosis and treatment of vestibular migraine - recent developments and future treatment strategies].

Laryngo- rhino- otologie·2026
Same journal

Laryngo- rhino- otologie·2026
Same journal

Laryngo- rhino- otologie·2026
Same journal

Laryngo- rhino- otologie·2026
See all related articles

Researchers developed a new colored microsphere technique to measure cochlear blood flow (CBF) in an animal model. This method allows for reproducible, absolute CBF measurements, aiding sudden hearing loss research.

Area of Science:

  • Otorhinolaryngology
  • Cardiovascular Physiology
  • Medical Imaging

Context:

  • Sudden hearing loss pathogenesis remains unknown, with vascular disturbances suspected but difficult to diagnose.
  • Current diagnostic methods lack the ability to clinically assess cochlear blood flow (CBF).
  • A reliable method to measure CBF is needed to investigate its role in sudden hearing loss.

Purpose:

  • To develop and validate a novel animal model for measuring cochlear blood flow (CBF).
  • To establish a reproducible technique for quantifying absolute CBF using colored microspheres.
  • To provide a tool for investigating the relationship between CBF and cochlear function.

Summary:

  • A new technique using colored microspheres was developed to measure cochlear blood flow (CBF) in an animal model (New Zealand rabbits).

Related Experiment Videos

  • The method involves injecting microspheres and calculating regional blood flow from trapped spheres and arterial samples.
  • Measurements demonstrated good reproducibility and allowed for absolute CBF quantification, with mean CBF values of 3.8 +/- 1.1 and 4.3 +/- 1.3 microliters/min at different time points.

    • Impact:

    • Enables precise, repeated measurements of cochlear blood flow (CBF) in vivo.
    • Provides a foundation for studying the role of vascular disturbances in sudden hearing loss.
    • Facilitates the determination of critical CBF thresholds for maintaining cochlear function.