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Synthesis and pharmacological properties of derivatives of isoxazolo[4,3-d]pyrimidine. III
E Wagner1, K Poreba, I Jakowicz
1Department of Technology of Drugs, Wroclaw University of Medicine, Poland.
Farmaco (Societa Chimica Italiana : 1989)
|March 1, 1995
Abstract:
Synthesis of new isoxazolo[4,5-d]pyrimidine derivatives is reported. Some of isoxazolo[4,5-d]pyrimidine derivatives were tested for anticonvulsant, anxiolytic and antiserotonine activity. Compounds 14 and 16 proved active against hypothermia induced by reserpine and hyperthermia induced by m-CPP.