Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Apoptosis--programmed cell death]

J Kvasnicka¹, J Petrásek

¹Oddĕlení klinické hematologie 1. LF UK a VFN, Praha.

Casopis Lekaru Ceskych

|May 3, 1995

Summary

This summary is machine-generated.

This study reviews programmed cell death (apoptosis) gene expression, covering both pro-apoptotic and anti-apoptotic factors. It explores therapeutic strategies for controlling apoptosis in diseases like cancer and AIDS.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Scintillation light detection in the 6-m drift-length ProtoDUNE Dual Phase liquid argon TPC.

The European physical journal. C, Particles and fields·2022

Same author

Late postoperative opacification of a hydrophobic acrylic intraocular lens AcryNovaTMPC 610Y.

Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti·2020

Same author

[Arthrodesis of Interphalangeal Joints of the Hand by an External Fixator in Managing Conditions Resulting from Septic Arthritis].

Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca·2019

Same author

Splanchnic vein closures.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2019

Same author

Tobacco smoking strongly modifies the association of prothrombin G20210A with undetermined stroke: consecutive survivors and population-based controls.

Atherosclerosis·2015

Same author

A randomised controlled trial of roller versus centrifugal cardiopulmonary bypass pumps in patients undergoing pulmonary endarterectomy.

Perfusion·2014

Area of Science:

Molecular Biology
Genetics
Cell Biology

Context:

Apoptosis, or programmed cell death, is a fundamental biological process.
Dysregulation of apoptosis is implicated in various diseases, including cancer, autoimmune disorders, and viral infections.
Understanding the genetic control of apoptosis is crucial for therapeutic interventions.

Purpose:

To summarize current knowledge on the genes regulating apoptosis.
To discuss the clinical implications of manipulating apoptotic pathways.
To highlight potential therapeutic targets for controlling programmed cell death.

Summary:

The review covers genes that promote apoptosis, such as p53, c-myc, MTS1, and Fas.
It also addresses genes that inhibit apoptosis, including bcl-2 and bcr-abl.

Related Experiment Videos

The authors examine the clinical applications of modulating apoptosis in oncology, autoimmune diseases, AIDS, and metabolic disorders.

Impact:

Provides a comprehensive overview of apoptosis regulation.
Identifies potential strategies for novel therapeutic approaches.
Facilitates a deeper understanding of disease mechanisms linked to apoptosis dysregulation.