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Updated: Jul 26, 2026

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Published on: August 26, 2014
Evaluation of the Steris System 1 Peracetic Acid Endoscope Processor
C R Bradley1, J R Babb, G A Ayliffe
1Hospital Infection Research Laboratory, City Hospital NHS Trust, Birmingham, UK.
The Steris System 1 Processor effectively kills bacteria and most spores using peracetic acid. This automated endoscope sterilizer offers staff safety but has higher costs than glutaraldehyde.
Area of Science:
- Microbiology
- Infection Control
- Biomedical Engineering
Background:
- Automated endoscope reprocessing is crucial for patient safety.
- Disinfection efficacy and material compatibility are key considerations for sterilizing machines.
Purpose of the Study:
- To evaluate the bactericidal and sporicidal efficacy of the Steris System 1 Processor.
- To assess the impact of the automated system on endoscope integrity.
Main Methods:
- Testing involved a 0.2% peracetic acid solution with a 12-minute exposure time.
- Bactericidal and sporicidal efficacy was assessed using suspension tests and contaminated endoscope simulations.
- Organisms tested included Pseudomonas aeruginosa, Staphylococcus aureus, and Bacillus subtilis spores.
Main Results:
- The system demonstrated significant log10 reduction (>5) of bacteria and P. aeruginosa in preliminary tests.
- No bacterial growth was observed on endoscopes after routine cycles.
- A small number of Bacillus subtilis survivors were detected on spore strips, indicating incomplete sporicidal action in some cases.
Conclusions:
- The Steris System 1 Processor shows high bactericidal efficacy and good performance against spores, though not absolute.
- The automated system enhances staff safety by minimizing direct exposure to disinfectants.
- While effective, the system's operational costs are higher than glutaraldehyde, and it lacks an integrated cleaning cycle.
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