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Dermatoglyphics in Down's syndrome

S Rajangam1, S Janakiram, I M Thomas

  • 1Department of Anatomy, St John's Medical College, Bangalore.

Journal of the Indian Medical Association
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

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Dermatoglyphics, the study of fingerprints, reveals significant differences in Down

Area of Science:

  • Genetics
  • Anthropology
  • Dermatoglyphics

Background:

  • Down syndrome is a genetic disorder associated with distinct physical features.
  • Dermatoglyphics offers a non-invasive method for studying genetic variations.

Purpose of the Study:

  • To investigate dermatoglyphic patterns in individuals with Down syndrome.
  • To compare these patterns with a control group.
  • To assess the clinical utility of dermatoglyphics in Down syndrome diagnosis.

Main Methods:

  • Dermatoglyphic prints were collected from 235 Down syndrome patients and 230 controls.
  • Methods included printing and transparent adhesive tape photography.
  • Analysis focused on total finger ridge counts, 'atd' angles, and pattern types.

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Main Results:

  • Significant differences were found in total finger ridge counts and 'atd' angles between Down syndrome patients and controls.
  • Ulnar loop patterns were predominant in the Down syndrome group.
  • Abnormal features like simian creases and Sydney lines were more frequent in patients.

Conclusions:

  • Dermatoglyphic analysis is valuable for identifying Down syndrome.
  • These findings support the use of dermatoglyphics in selecting patients for cytogenetic analysis.
  • Dermatoglyphic markers can aid in the early identification and diagnosis of Down syndrome.