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[Effects of propofol in patients in status epilepticus of various origins. Electroencephalographic analysis]
A Mazzarino1, G De Maria, A Candiani
1Cattedra di Anestesia e Rianimazione, Università degli Studi, Brescia.
Abstract:
The authors discuss the effect of propofol administered to epileptic patients in intensive care. Several reports have attributed and antiepileptic effect to this drug, whereas a similar number have correlated it to epileptogenic manifestations of various types. Three "typical" cases of epilepsy were studied: chronic postoperative, chronic and acute post-traumatic. EEG patterns were analysed following continuous administration, using a bolus and using varying doses of the drug itself. Propofol appears to modify EEG patterns in a positive manner and is therefore confirmed as being useful in the sedation of epileptic patients in intensive care.