Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Psychotropic drug-induced myoclonus]

K E Brogmus1, A Lesch

  • 1Evangelische Nervenklinik, Klinikbereich Neurologie, Remscheid-Lüttringhausen.

Psychiatrische Praxis
|March 1, 1995
PubMed
Summary

Antidepressant or neuroleptic-induced myoclonus may indicate increased cerebral excitability or epilepsy. Further neurophysiological testing, including electroencephalography (EEG) and somatosensory evoked potentials (SSEP), can help assess seizure risk.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"There is not a safe space where they can find themselves to be free": (Un)safe spaces and the promotion of queer visibilities among township males who have sex with males (MSM) in Cape Town, South Africa.

Health & place·2017
Same author

The antioxidant capacity of erythrocyte concentrates is increased during the first week of storage and correlated with the uric acid level.

Vox sanguinis·2017
Same author

Is participation in HIV vaccine trials a health promoting behaviour?

AIDS care·2007
Same author

Paediatric HIV/AIDS disclosure: towards a developmental and process-oriented approach.

AIDS care·2007
Same author

[Lithium and hyperthyroidism].

Psychiatrische Praxis·1993
Same author

The diencephalon in schizophrenia: evidence for reduced thickness of the periventricular grey matter.

European archives of psychiatry and neurological sciences·1984

Area of Science:

  • Neurology
  • Neurophysiology
  • Epileptology

Background:

  • Myoclonus can be a symptom of various neurological conditions.
  • Distinguishing drug-induced myoclonus from other causes is crucial for diagnosis and management.
  • Increased cerebral excitability may underlie certain types of myoclonus.

Observation:

  • Five case studies explored the link between drug-induced myoclonus and epilepsy.
  • Electroencephalography (EEG) recordings in reported cases showed epilepsy-specific potentials.
  • Somatosensory evoked potentials (SSEP) revealed N1/P1 amplitude increases.

Findings:

  • Drug-induced myoclonus, when physiological causes are excluded, often suggests subtle signs of increased cerebral excitability.
  • This presentation can represent an epileptic fragment or, in some cases, myoclonus epilepsy.
  • EEG and SSEP findings may serve as diagnostic criteria for seizure risk assessment.

Implications:

  • Further neurophysiological examinations, particularly back-averaging techniques, are recommended for comprehensive evaluation.
  • EEG and SSEP analysis can aid in determining the risk of epileptic seizures associated with specific myoclonus types.
  • These findings underscore the importance of considering drug-induced myoclonus as a potential indicator of underlying epileptiform activity.

Related Experiment Videos