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Stenosis of the Inferior Vena Cava: A Murine Model of Deep Vein Thrombosis
05:37

Stenosis of the Inferior Vena Cava: A Murine Model of Deep Vein Thrombosis

Published on: December 22, 2017

Inferior vena cava thrombosis as a complication of femoral vein catheterisation

A Shefler1, J Gillis, A Lam

  • 1Children's Hospital, Camperdown, NSW, Australia.

Archives of Disease in Childhood
|April 1, 1995
PubMed

Insights

Inferior vena cava (IVC) thrombosis occurred in 6 of 56 pediatric patients with femoral venous catheters. Early detection via ultrasound or catheter replacement at six days is recommended to prevent complications.

Area of Science:

  • Pediatric Medicine
  • Vascular Surgery
  • Diagnostic Imaging

Background:

  • Indwelling femoral venous catheters are crucial for pediatric patient care.
  • Catheter-related thrombosis, particularly in the inferior vena cava (IVC), poses a significant risk.
  • Early identification and management of IVC thrombosis are essential to prevent adverse events.

Purpose of the Study:

  • To prospectively evaluate the frequency and progression of IVC thrombosis in children with indwelling femoral venous catheters.
  • To determine the correlation between catheter dwell time and the incidence of IVC thrombosis.
  • To assess the clinical presentation of IVC thrombosis in this patient population.

Main Methods:

  • Prospective ultrasonographic study of 56 pediatric patients with indwelling femoral venous catheters.
  • Identification and documentation of IVC thrombosis using ultrasound.
  • Correlation of ultrasound findings with clinical signs and symptoms.

Main Results:

  • IVC thrombosis was detected in 6 out of 56 catheters (10.7%) in 54 children.
  • Only one child with confirmed IVC thrombosis exhibited clinical signs.
  • All identified cases of IVC thrombosis were associated with catheters in place for more than six days.

Conclusions:

  • Routine ultrasound screening twice weekly for catheters in situ for over six days is recommended.
  • Alternatively, consider routine replacement of femoral central venous catheters at six days.
  • Immediate catheter removal upon detection of IVC thrombosis is advised to mitigate risks.

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