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Update on cholesterol and the eye

J H Nishimoto1

  • 1Southern California College of Optometry, Fullerton, USA.

Optometry Clinics : the Official Publication of the Prentice Society
|January 1, 1995
PubMed
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High cholesterol is a risk factor for heart disease. Eye care practitioners can identify corneal signs indicating high cholesterol, prompting referral for lipid evaluation and management.

Area of Science:

  • Ophthalmology
  • Cardiology
  • Metabolic Disorders

Background:

  • High serum cholesterol is a significant risk factor for cardiovascular disease and arteriosclerosis.
  • Ocular manifestations can serve as indicators of systemic lipid abnormalities.
  • Early detection through eye examinations can facilitate timely medical intervention.

Purpose of the Study:

  • To describe the corneal signs associated with abnormal cholesterol levels.
  • To provide guidance for eye care practitioners in managing patients with these findings.
  • To emphasize the role of ophthalmology in identifying potential cardiovascular risks.

Main Methods:

  • Review of clinical signs and diagnostic criteria for corneal manifestations of hyperlipidemia.
  • Analysis of case studies illustrating the link between corneal findings and serum cholesterol.

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  • Development of a management algorithm for eye care professionals.

    • Main Results:

    • Specific corneal signs, such as arcus senilis and xanthelasma, are correlated with elevated cholesterol levels.
    • These ocular findings can precede or coincide with diagnosed cardiovascular conditions.
    • Prompt referral based on corneal signs can lead to the diagnosis of dyslipidemia.

    Conclusions:

    • Corneal manifestations are valuable indicators of underlying high cholesterol.
    • Eye care practitioners play a crucial role in the early detection of lipid disorders.
    • Integrating lipid evaluation into routine eye care can improve patient outcomes and reduce cardiovascular risk.