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[Hormone therapy in breast cancer]
1Centre René-Huguenin, Chirurgie, Saint-Cloud.
Chirurgie; Memoires De L'Academie De Chirurgie
|January 1, 1994
Summary
Hormonotherapy remains a vital breast cancer treatment, particularly for hormone receptor-positive cases. This approach, including tamoxifen and castration, shows significant tumor regression and is crucial for elderly patients with metastases.
Area of Science:
- Oncology
- Endocrinology
Context:
- Hormonotherapy is the longest-standing effective medical intervention for breast cancer.
- Its efficacy is well-established, with significant tumor regression rates in hormone-dependent breast cancers.
Purpose:
- To review the current applications and effectiveness of various hormonotherapy treatments for breast cancer.
- To highlight the precise indications for hormonotherapy in different patient populations and disease stages.
Summary:
- Hormonotherapy, including anti-oestrogen agents like tamoxifen and castration methods, demonstrates effectiveness in treating breast cancer.
- Adjuvant therapy guidelines suggest castration before menopause and tamoxifen after menopause.
- Hormonotherapy is particularly beneficial for elderly women with metastatic, hormone receptor-positive breast cancer.
Impact:
- Hormonotherapy continues to be a cornerstone in breast cancer management, especially for hormone receptor-positive tumors.
- Precise indications enhance treatment outcomes and patient selection.
- Further research is needed to define its role within comprehensive chemotherapy regimens.