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Published on: February 18, 2015
Infections of the head and neck in diabetes mellitus
1Harvard Medical School, Boston, Massachusetts, USA.
Abstract:
Patients with diabetes mellitus exhibit particular susceptibility to three severe infections of the head and neck: rhinocerebral mucormycosis, postoperative endophthalmitis, and malignant otitis externa. Rhinocerebral mucormycosis is an extensive life-threatening infection beginning in the nasal passages and sinuses and extending often into the orbit and the cerebrum. Endophthalmitis, which is infection of the vitreal contents, can occur secondary to bacteremia, trauma, or postoperatively. Invasive external otitis or malignant otitis externa is an invasive infection beginning in the adjacent soft tissue and into bone. It is usually secondary to Pseudomonas aeruginosa and occurs almost exclusively in diabetics. These will all be discussed in this article.
Insights
Diabetic patients are highly susceptible to severe head and neck infections, including rhinocerebral mucormycosis, postoperative endophthalmitis, and malignant otitis externa. This article details these serious diabetic-associated infections.
Area of Science:
- Infectious Diseases
- Ophthalmology
- Otolaryngology
Background:
- Diabetes mellitus compromises immune function, increasing susceptibility to severe infections.
- Head and neck infections pose significant risks for diabetic patients.
- Specific infections discussed include rhinocerebral mucormycosis, postoperative endophthalmitis, and malignant otitis externa.
Purpose of the Study:
- To discuss severe head and neck infections in diabetic patients.
- To provide an overview of rhinocerebral mucormycosis, postoperative endophthalmitis, and malignant otitis externa.
- To highlight the particular vulnerability of individuals with diabetes mellitus to these conditions.
Main Methods:
- Literature review and synthesis of existing knowledge.
- Discussion of the pathophysiology and clinical presentation of each infection.
- Emphasis on the association between diabetes mellitus and these infections.
Main Results:
- Rhinocerebral mucormycosis is a life-threatening fungal infection originating in the sinuses.
- Postoperative endophthalmitis is an intraocular infection that can lead to vision loss.
- Malignant otitis externa, often caused by Pseudomonas aeruginosa, is a severe infection of the ear and surrounding bone, predominantly seen in diabetics.
Conclusions:
- Diabetic patients face elevated risks for specific, severe head and neck infections.
- Early recognition and management are crucial for improving outcomes in these patients.
- Understanding the link between diabetes and these infections is vital for healthcare providers.
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