Related Experiment Videos
Free radicals and ocular disease
R E Anderson1, F L Kretzer, L M Rapp
1Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA.
Advances in Experimental Medicine and Biology
|January 1, 1994
Summary
Dietary intake of fruits and vegetables rich in antioxidants is low. Antioxidant supplementation may help prevent age-related degenerative diseases and ocular disorders.
Area of Science:
- Nutrition Science
- Ophthalmology
- Gerontology
Background:
- Degenerative diseases of aging are linked to oxidants and antioxidants.
- Most Americans do not consume recommended daily servings of fruits and vegetables.
- Antioxidants and micronutrients in these foods play a vital role in health.
Purpose of the Study:
- To review the relationship between oxidants, antioxidants, and age-related degenerative diseases.
- To highlight the low intake of antioxidant-rich foods in the American diet.
- To discuss preventive measures for ocular disorders linked to free radical damage.
Main Methods:
- Literature review of studies on oxidants, antioxidants, and degenerative diseases.
- Analysis of dietary intake data regarding fruit and vegetable consumption.
- Examination of clinical, basic, and epidemiological research on ocular disorders and lipid peroxidation.
Main Results:
- A significant gap exists between recommended and actual daily intake of fruits and vegetables.
- Free radical-induced lipid peroxidation is implicated in various ocular disorders.
- No official recommendations for antioxidant supplementation exist from governmental or professional bodies.
Conclusions:
- Prudent measures for individuals at risk of age-related degenerative diseases and ocular disorders are recommended.
- Protective strategies include UV-filtering sunglasses, protective hats, and increased consumption of fruits, vegetables, and antioxidants.