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Tissue- and development-specific expression of goat insulin-like growth factor-I (IGF-I) mRNAs
S Mikawa1, G Yoshikawa, Y Yamano
1Department of Agricultural Chemistry, Kyoto University, Japan.
Bioscience, Biotechnology, and Biochemistry
|April 1, 1995
Abstract:
We cloned four kinds of goat insulin-like growth factor-I (IGF-I) cDNAs. Each of them encodes the same mature IGF-I and different signal peptides. In this study, we analyzed expression of the four kinds of mRNAs in tissues in various developmental stages by a reverse transcriptase-polymerase chain reaction assay. The results suggest that their expression may be controlled by different promoters, the activities of which are tissue- and development-specific.