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The fungal cell wall as a drug target
N H Georgopapadakou1, J S Tkacz
1Dept of Oncology, Roche Research Center, Nutley, NJ 07110, USA.
Trends in Microbiology
|March 1, 1995
Abstract:
Fungal infections are increasingly common and, in certain vulnerable patients, can be serious and even life threatening. The fungal cell wall, a structure with no mammalian counterpart, presents an attractive therapeutic target. Inhibitors of the synthesis of one cell-wall component, beta-(1,3)-glucan, are currently under development as antifungal and antipneumocystis agents.