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[Dynamic cardiomyoplasty: first successful clinical case in China]
Abstract:
A 35-year-old man with chronic heart failure (NYHA Class III) caused by dilated cardiopathy was selected for dynamic cardiomyoplasty. The procedures were completed in one stage. The left latissimus dorsi muscle was mobilized and wrapped around the heart. A set of medtronic cardiomyostimulator system (A Medtronic Model SP 1005A Cardiomyostimulator, two Medtronic Model SP 5528 intramuscular leads, and two medtronic Model 5701-35 Cardiac screw-in leads) was implanted. The postoperative sequential progressive skeletal muscle electrostimulation was started two weeks after cardiomyoplasty. The final electrostimulated parameters were: 6 pulses, amplitude 2.75 V, synchronization delay 75 ms, pulse width 210 us, synchronization delay 75 ms, pulse width 210 us, synchronization ratio 2:1, frequency 30 Hz, stimulation duration 185 ms. The patient recovered very well. After four months, patient's status improved to NYHA Class I. Echocardiography, MUGA, and catheterization studies showed a significant improvement in hemodynamic parameters (MUGA LVEF increased from 15% to 24%, SVI increased from 21.7 ml/beat/m2 to 50.6 ml/beat/m2: CI increased from 2.699 L/min/m2 to 3.59 L/min/m2.