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Cancer. A potentially preventable disease

C G Kardinal1

  • 1Ochsner Cancer Institute, Ochsner Clinic, New Orleans, USA.

The Journal of the Louisiana State Medical Society : Official Organ of the Louisiana State Medical Society
|April 1, 1995
PubMed
Summary
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Most cancers are preventable by identifying and removing specific causes, like tobacco smoke. New chemo-prevention strategies are also being explored, including hormonal agents and vitamin A analogs.

Area of Science:

  • Oncology
  • Epidemiology
  • Preventive Medicine

Background:

  • Growing evidence suggests specific causes for individual cancers.
  • This implies that most cancers are potentially preventable.
  • Primary prevention, by removing etiological agents, is the most effective strategy.

Purpose of the Study:

  • To highlight the potential for cancer prevention.
  • To discuss primary prevention strategies, such as eliminating tobacco smoke.
  • To introduce emerging chemo-prevention techniques.

Main Methods:

  • Review of current epidemiologic data.
  • Analysis of carcinogenesis research.
  • Evaluation of hormonal agents, anti-inflammatory drugs, and vitamin A analogs for chemo-prevention.

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Main Results:

  • Epidemiologic and carcinogenesis data support the hypothesis of specific cancer causes.
  • Elimination of etiological agents like tobacco smoke is a key primary prevention method.
  • Chemo-prevention agents are under investigation as secondary prevention strategies.

Conclusions:

  • Most cancers are preventable through targeted interventions.
  • Primary prevention by removing specific causes is paramount.
  • Chemo-prevention offers a promising avenue for cancer risk reduction.