Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optimizing defibrillation through improved waveforms

M Block1, G Breithardt

  • 1Hospital of the Westfälische Wilhelms-University of Münster, Department of Cardiology/Angiology, Germany.

Pacing and Clinical Electrophysiology : PACE
|March 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Detection of circulating cerebral microemboli by transcranial Doppler ultrasonography].

Zeitschrift fur Kardiologie·2001
Same author

Intracardiac tuberculoma causing "idiopathic" ventricular tachycardia in a patient without detectable heart disease.

Journal of cardiovascular electrophysiology·2001
Same author

Impact of radiofrequency catheter ablation of accessory pathways on the frequency of atrial fibrillation during long-term follow-up; high recurrence rate of atrial fibrillation in patients older than 50 years of age.

European heart journal·2001
Same author

Pulmonary beta adrenoceptor density in arrhythmogenic right ventricular cardiomyopathy and idiopathic tachycardia.

Basic research in cardiology·2001
Same author

Signal characteristics of multichannel epicardial electrograms in chronic ischaemic and scarred myocardium: electromechanical mismatch indicates viability in regions of myocardial dysfunction.

Basic research in cardiology·2001
Same author

xIAP induces cell-cycle arrest and activates nuclear factor-kappaB : new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells.

Circulation research·2001
Same journal

A Case of Permanent Pacemaker Implantation via the Epicardial Approach Using the 3830 Lead in an 11-Day-Old Neonate (With Follow-Up of the Above Case).

Pacing and clinical electrophysiology : PACE·2026
Same journal

Cryoballoon Versus Radiofrequency Ablation for Persistent Atrial Fibrillation: Meta-Analysis of Randomized Trials.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Tilt Test Duration in Suspected Vasovagal Syncope: Temporal Patterns and Diagnostic Yield in Patients From Central China.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Combined Leadless Pacing and Subcutaneous ICD Therapy in Long QT Syndromes.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Association of Anesthesia Modality With Procedural Parameters and Clinical Outcomes in PVI for Atrial Fibrillation.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Zero-Fluoroscopy Cryoballoon Ablation for Paroxysmal Atrial Fibrillation in a Patient With Dextrocardia: A Case Report.

Pacing and clinical electrophysiology : PACE·2026
See all related articles

Biphasic waveforms using approximately 90-microfarad capacitors and bipolar lead systems optimize defibrillation energy, capacitor size, and implantation ease. This approach improves defibrillation success rates and reduces energy requirements.

Area of Science:

  • Cardiovascular Electrophysiology
  • Medical Device Engineering

Background:

  • Defibrillation requires high electrical current to depolarize myocardial cells.
  • Capacitors are crucial for delivering the high voltage needed for defibrillation.
  • Traditional monophasic waveforms have limitations in energy efficiency.

Purpose of the Study:

  • To explore waveform modifications for optimizing defibrillation energy requirements.
  • To evaluate the impact of capacitance, waveform duration, and polarity on defibrillation efficacy.
  • To determine the optimal configuration for modern defibrillators.

Main Methods:

  • Investigated changes in capacitance, waveform duration (tilt), and polarity.
  • Compared monophasic, biphasic, and triphasic waveforms.

Related Experiment Videos

  • Analyzed energy requirements and defibrillation success with different capacitor values (125 microF, 60-90 microF).

    • Main Results:

    • Biphasic and triphasic waveforms significantly lower energy needs compared to monophasic.
    • Reversing initial polarity and polarity during discharge enhances defibrillation success.
    • Approximately 90-microfarad capacitors are optimal for biphasic pulses with bipolar leads.

    Conclusions:

    • Modern defibrillation is optimized using biphasic pulses with ~90 microF capacitors and bipolar leads.
    • This configuration balances energy efficiency, device size, and ease of implantation.
    • Optimized waveforms prevent defibrillation failures and improve patient outcomes.