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Updated: Aug 17, 2026

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
Published on: November 3, 2012
[Studies on red blood cell-mediated immunity of patients with recurrent stromal herpes simplex keratitis]
1Institute of Ophthalmology, Shandong Academy of Medical Sciences, Qingdao.
Abstract:
Assays of red blood cell (RBC) C3b receptor rosette and RBC immune complex (IC) rosette of 67 cases with recurrent stromal herpes simplex keratitis (HSK) were carried out. The results show that the rosette rate of RBC C3b receptor is markedly lowered and that of RBC IC receptor is significantly increased in cases with stromal HSK. In comparisons with the corresponding rates in the control group, there are significant differences (P < 0.01). The roles of RBC-mediated immunity in the immunopathogenesis of HSK were preliminarily discussed.
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