Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Superficial mycoses

D Taplin

    The Journal of Investigative Dermatology
    |July 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Advances in antifungal treatments have improved superficial mycoses care. Griseofulvin and newer agents like imidazoles offer effective therapies for fungal infections, though diagnosis and prevention remain key.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Genetic epidemiology of Sarcoptes scabiei (Acari: Sarcoptidae) in northern Australia.

    International journal for parasitology·2004
    Same author

    Dermatophytosis in Vietnam.

    Cutis·2001
    Same author

    Dermatophytosis in Vietnam, Part 2.

    Cutis·2001
    Same author

    Genetically distinct dog-derived and human-derived Sarcoptes scabiei in scabies-endemic communities in northern Australia.

    The American journal of tropical medicine and hygiene·1999
    Same author

    Age, renal perfusion and function in island-dwelling indigenous Kuna Amerinds of Panama.

    Nephron·1999
    Same author

    Isolation, amplification, and sequencing of human mitochondrial DNA obtained from human crab louse, Pthirus pubis (L.), blood meals.

    Journal of forensic sciences·1998
    Same journal

    An Integrated Skin Cell Atlas Decodes the Pilosebaceous Unit.

    The Journal of investigative dermatology·2026
    Same journal

    Residual CSB activity explains mild UV-sensitive syndrome phenotype caused by CSB mutations.

    The Journal of investigative dermatology·2026
    Same journal

    Charting a new melanoma risk factor: Satellite Naevus Prevalence in High-Risk and Population-Based Cohorts.

    The Journal of investigative dermatology·2026
    Same journal

    Human keratinocytes and fibroblasts coordinate early cutaneous innate defenses against Candida auris.

    The Journal of investigative dermatology·2026
    Same journal

    Merkel cells attenuate autoantigen-specific T cell driven skin inflammation in mice associated with reduced neutrophil recruitment.

    The Journal of investigative dermatology·2026
    Same journal

    The response of human melanocytic nevi to simulated solar radiation assessed by single-nucleus RNA sequencing of frozen tissue.

    The Journal of investigative dermatology·2026
    See all related articles

    Area of Science:

    • Dermatology and Mycology
    • Infectious Diseases
    • Pharmacology

    Background:

    • Historical limitations of topical antifungal remedies included irritation, toxicity, and allergenicity.
    • Scalp x-ray depilation was a common, albeit harsh, treatment for tinea capitis.
    • Early topical agents like nystatin and tolnaftate represented progress but did not fully resolve challenging fungal infections.

    Purpose of the Study:

    • To review the evolution of antifungal therapies for superficial mycoses.
    • To highlight key advancements in treating dermatophytosis, candidiasis, and related conditions.
    • To discuss the impact of environmental and host factors on fungal infection prevalence.

    Main Methods:

    • Review of historical and recent developments in antifungal medications.

    Related Experiment Videos

  • Analysis of therapeutic outcomes for various superficial fungal infections.
  • Examination of epidemiological data, particularly from Vietnam, on mycoses prevalence.

    • Main Results:

    • Griseofulvin (introduced in 1958) became a cornerstone treatment for dermatophytosis, significantly reducing tinea capitis epidemics.
    • Introduction of topical haloprogin and imidazole derivatives (miconazole, clotrimazole) expanded treatment options for dermatophytes and Candida albicans.
    • Epidemiological studies underscored the influence of climate and occlusion on superficial mycoses, prompting interest in host susceptibility and prevention.

    Conclusions:

    • Significant progress has been made in topical and systemic antifungal treatments over the past 25 years.
    • While effective treatments exist, challenges remain in diagnosing and preventing superficial fungal infections.
    • Further research into host-pathogen interactions and environmental influences is crucial for comprehensive management strategies.