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Related Experiment Videos

Group B streptococcal colonization in pregnancy

V Schauf, V Hlaing

    Obstetrics and Gynecology
    |June 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Group B Streptococcus (GBS) colonization in pregnant women is linked to newborn infection. Oral contraceptive use may increase GBS colonization risk, but treatment for carriers might not always be necessary.

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    Area of Science:

    • Obstetrics and Gynecology
    • Neonatal Medicine
    • Infectious Diseases

    Background:

    • Group B beta-hemolytic streptococcal (GBS) infection in newborns, acquired from the maternal genital tract, is a significant cause of illness and death.
    • The degree of maternal GBS colonization may influence the risk of infant colonization and infection.

    Purpose of the Study:

    • To determine the prevalence of genital tract colonization with GBS in pregnant women.
    • To investigate potential risk factors for GBS colonization, such as oral contraceptive use.
    • To assess the natural clearance rate of GBS colonization in untreated pregnant women.

    Main Methods:

    • A semiquantitative assessment of genital tract colonization was performed in 210 pregnant women.
    • Colonization levels were determined by bacterial colony counts per sample.

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  • Follow-up cultures were obtained for a subset of untreated colonized women.

    • Main Results:

    • Twelve women (6%) were found to be colonized with GBS.
    • Women who used oral contraceptives in the year prior to pregnancy had a higher rate of GBS colonization (70%) compared to uncolonized women (35%).
    • A higher GBS colony count was inversely related to the duration of pregnancy. Six of nine untreated colonized women had negative repeat cultures.

    Conclusions:

    • Oral contraceptive use may be associated with an increased risk of GBS colonization in pregnant women.
    • Untreated GBS colonization in pregnant women may be transient, suggesting that routine treatment might not be universally required.
    • Further research is needed to fully understand the implications of GBS colonization and its management during pregnancy.