["In vitro" effect of medium size molecules on lymphocyte proliferation (author's transl)]

Eluates from uremic sera were obtained by chromatography on sephadex G 25. They were assayed on lymphocytes cultured in the presence of various stimulants. Lymphocyte proliferation induced by mitogens or allogeneic cells was markedly inhibited in the presence of medium size molecules (MM), or of larger molecules (MW greater than 5000).