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Adjunctive therapy in epilepsy: a cost-effectiveness comparison of alternative treatment options
B A O'Neill1, M R Trimble, D S Bloom
1Arthur D. Little Ltd, Berkley Square, London, UK.
Seizure
|March 1, 1995
Abstract:
A pharmaco-economic study of the administration of adjunctive therapy in patients with chronic epilepsy is described. A decision-analytic model has been used, which represents the consequences of treatment over a 1-year time period, when one of three drugs is used first. The cost-effectiveness ratio for clobazam, lamotrigine and vigabatrin have been calculated. The expected cost per patient of treatment over the 1-year period was up to 50% higher with vigabatrin and lamotrigine compared with clobazam, with a cost-effectiveness ratio around 40% higher.