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A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
Prevalence of depression after stroke: the Perth Community Stroke Study
P W Burvill1, G A Johnson, K D Jamrozik
1Department of Psychiatry and Behavioural Science, University of Western Australia, Perth.
Depression is common after stroke, affecting 23% of patients at four months and persisting long-term, particularly in men. This study analyzed depression prevalence in stroke survivors.
Area of Science:
- Neurology
- Psychiatry
- Epidemiology
Background:
- The Perth Community Stroke Study (PCSS) investigated acute stroke incidence, causes, and outcomes.
- Population-based research is crucial for understanding stroke's impact.
Purpose of the Study:
- To determine the prevalence of depression after stroke.
- To compare depression rates between sexes and stroke types (first-ever vs. recurrent).
Main Methods:
- Initial assessment, plus 4- and 12-month follow-ups.
- Interviews and examinations were used to diagnose depression.
- Analysis included 294 stroke patients from the PCSS.
Main Results:
- Four months post-stroke, 23% had depressive illness (15% major, 8% minor).
- Men showed higher rates of persistent depression at 12 months (56%) compared to women (30%).
- No significant differences in depression prevalence were found between sexes or stroke types initially.
Conclusions:
- Post-stroke depression prevalence is comparable to other studies.
- Depression rates were lower than those reported in inpatient or rehabilitation settings.
- Anxiety disorders frequently co-occurred with depression in stroke survivors.
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