Related Experiment Videos
Candida chorioretinitis in meningococcal meningitis
R Maddaluno1, C Nobili, P Cocucci
1Department of Infectious Diseases, Hospital of Frosinone.
La Clinica Terapeutica
|February 1, 1995
Summary
This case report details Candida chorioretinitis in a meningococcal meningitis patient. High-dose intravenous fluconazole treatment led to significant visual recovery, improving prognosis.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Mycology
Background:
- Meningococcal meningitis can predispose patients to opportunistic infections.
- Corticosteroid and antibiotic treatments for meningitis may increase the risk of fungal infections.
Observation:
- A patient with meningococcal meningitis developed oropharyngeal candidiasis and subsequent ocular symptoms including pain, blurred vision, and positive scotoma.
- Ophthalmoscopic examination indicated probable Candida chorioretinitis.
Findings:
- Intravenous fluconazole administered at high doses was used to treat the Candida chorioretinitis.
- The treatment resulted in complete visual recovery in the right eye and partial recovery (2/10 visual acuity) in the left eye.
Implications:
- This case highlights the potential for Candida chorioretinitis in immunocompromised patients with meningitis.
- Long-term, high-dose fluconazole therapy, typically used for systemic mycoses, shows promise in improving outcomes for ocular fungal infections.