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[Keratoacanthoma centrifugum marginatum]

M Chaffai1, M H Houman, S Haouet

  • 1Polyclinique Ettaoufki, Hôpital La Rabta, Tunis.

Annales De Dermatologie Et De Venereologie
|January 1, 1994
PubMed
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This study reports a successful treatment for a rare skin condition, keratoacanthoma centrifugum marginatum (KCM), using etretinate. This medical therapy offered an alternative to surgery for KCM and improved associated psoriasis vulgaris.

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Keratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma.
  • Surgical excision is the primary treatment but is challenging due to lesion extent.

Observation:

  • A patient with a year-long history of KCM and psoriasis vulgaris was treated.
  • The patient received etretinate at 1 mg/kg/day for five months.

Findings:

  • Successful treatment of KCM with etretinate was achieved.
  • Etretinate therapy also led to the remission of the patient's psoriasis vulgaris.
  • This medical approach avoided the need for conventional surgery.

Implications:

  • Etretinate demonstrates potential as an effective alternative to surgical treatment for KCM, especially when associated with psoriasis.

Related Experiment Videos

  • This case highlights a novel therapeutic option for a rare and challenging skin condition.
  • Further research into retinoid therapy for KCM is warranted.