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Related Experiment Videos

Mediastinal lymph node size in an Asian population

J G Murray1, M O'Driscoll, J J Curtin

  • 1Radiology Department, Northwick Park Hospital, Harrow, Middlesex, UK.

The British Journal of Radiology
|April 1, 1995
PubMed
Summary
This summary is machine-generated.

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Mediastinal lymph node size in Asian patients with previous tuberculosis was assessed. The study found that standard size criteria for lymph node enlargement are applicable for staging thoracic cancers in this population.

Area of Science:

  • Radiology and Imaging
  • Thoracic Oncology
  • Infectious Diseases

Background:

  • High incidence of respiratory tuberculosis in British Asian populations.
  • Granulomatous diseases, like tuberculosis, can cause persistent lymph node enlargement.
  • Potential need for distinct computed tomography (CT) criteria for nodal size in Asian patients undergoing thoracic malignancy staging.

Purpose of the Study:

  • To measure mediastinal lymph node size in an Asian population.
  • To correlate lymph node size with a history of tuberculosis.
  • To determine if current lymph node size criteria for malignancy staging are appropriate for Asian patients.

Main Methods:

  • Review of chest CT scans from 48 Asian patients over 5 years.
  • Exclusion of patients with pulmonary disease, malignancy, or distorted anatomy.

Related Experiment Videos

  • Measurement of all lymph nodes and recording of sizes >7 mm using the American Thoracic Society (ATS) lymph node map.

    • Main Results:

    • 81.3% of patients had nodes ≤7 mm at all ATS stations.
    • Nodes >7 mm were primarily located in regions 4R, 10R, and 7.
    • 50% of patients with prior tuberculosis had nodes >7 mm, versus 6% without (p < 0.001).

    Conclusions:

    • Despite differences in nodal size related to tuberculosis history, only 8.3% of patients had nodes >10 mm.
    • The generally accepted criterion of >10 mm for mediastinal lymph node enlargement is applicable to Asian patients.
    • Standard CT criteria can be used for staging lymphoma or bronchogenic carcinoma in Asian populations.