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Can the radiologist recognize Helicobacter pylori gastritis?
D J Mond1, R Pochaczevsky, F Vernace
1Department of Radiology, Long Island Jewish Medical Center, Long Island Campus for the Albert Einstein College of Medicine, New Hyde Park, New York, USA.
Journal of Clinical Gastroenterology
|April 1, 1995
Summary
Enlarged gastric folds in upper gastrointestinal series are highly suggestive of Helicobacter pylori (H. pylori) infection. This finding aids in diagnosing H. pylori gastritis in symptomatic adults.
Area of Science:
- Radiology
- Gastroenterology
- Infectious Diseases
Background:
- Helicobacter pylori (H. pylori) infection is a common cause of upper gastrointestinal issues.
- Radiographic findings of H. pylori gastritis are not well-established.
Purpose of the Study:
- To evaluate the radiologic findings of H. pylori in the upper gastrointestinal tract.
- To determine the association between enlarged gastric folds and H. pylori infection.
Main Methods:
- Retrospective review of 676 symptomatic adults with gastric biopsies and 150 with rapid urease tests.
- Blind evaluation of upper gastrointestinal (UGI) series by two radiologists.
- Comparison of UGI findings in H. pylori-positive versus H. pylori-negative patients.
Main Results:
- Abnormally increased gastric folds were observed in 44% of H. pylori-positive UGI series, compared to 0% in H. pylori-negative cases (p < 0.01).
- High positive predictive value (1.0) for enlarged gastric folds indicating H. pylori infection.
- Endoscopy confirmed significant abnormalities in all patients with radiographic evidence of enlarged folds.
Conclusions:
- Enlarged gastric folds on UGI series are highly suggestive of H. pylori gastritis in symptomatic adults.
- Radiographic detection of enlarged gastric folds can aid in diagnosing H. pylori infection.