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A patient experienced digital pain after ganglion excision due to hyperplastic Pacinian corpuscles. These specialized nerve endings were found to be compressing the digital nerve, causing the pain.

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Area of Science:

  • Neuroscience
  • Pathology

Background:

  • Palmar ganglions are common cystic swellings.
  • Digital pain can occur post-surgery.

Observation:

  • A 68-year-old female presented with acute digital pain following palmar ganglion excision.
  • A mass of hyperplastic Pacinian corpuscles was identified as the cause of nerve compression.

Findings:

  • Immunohistochemistry revealed neuropeptide expression in the hyperplastic Pacinian corpuscles.
  • Pacinian corpuscle hyperplasia was compressing the digital nerve, leading to pain.

Implications:

  • This case highlights an unusual cause of post-operative digital pain.
  • Understanding Pacinian corpuscle hyperplasia mechanisms may inform future treatments.