Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Needle modifications for invasive fetal procedures

C R Welch1, D G Talbert, R M Warwick

  • 1Institute of Obstetrics and Gynaecology, Royal Postgraduate Medical School, University of London, Queen Charlotte's & Chelsea Hospital, United Kingdom.

Obstetrics and Gynecology
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantifying structural redundancy in ecological communities.

Oecologia·2017
Same author

The influence of temperature and salinity on energy partitioning in the marine nematode Diplolaimelloides bruciei.

Oecologia·2017
Same author

The effect of temperature on the respiration rate of meiofauna.

Oecologia·2017
Same author

Species size distributions in marine benthic communities.

Oecologia·2017
Same author

The size distribution of organisms in the Celtic Sea: from bacteria to Metazoa.

Oecologia·2017
Same author

Total uterine artery blood volume flow rate in nulliparous women is associated with birth weight and gestational age at delivery.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2016
Same journal

The Political Determinants of Obstetric Prescribing.

Obstetrics and gynecology·2026
Same journal

Glucagon-Like Peptide-1 Receptor Agonists and Risk of Adverse Maternal Pregnancy Outcomes: A Systematic Review and Meta-analysis.

Obstetrics and gynecology·2026
Same journal

Milestones in Motion: Vaginal Birth After Cesarean.

Obstetrics and gynecology·2026
Same journal

Ebola Virus in Pregnancy.

Obstetrics and gynecology·2026
Same journal

A Quality-Improvement Study Evaluating Three Postpartum Prophylactic Oxytocin Rates and Blood Loss After Vaginal Birth.

Obstetrics and gynecology·2026
Same journal

The Effects of Climate Change on Obstetric and Gynecologic Health.

Obstetrics and gynecology·2026
See all related articles

Modified needles improve fetal blood sampling and transfusion by increasing flow and reducing clots. Teflon-coated needles also enabled direct fetal electrocardiography (ECG) recordings.

Area of Science:

  • Perinatal Medicine
  • Medical Device Engineering

Background:

  • Fetal blood sampling and transfusion are critical procedures in managing high-risk pregnancies.
  • Standard needles can face challenges with blood flow, clotting, and signal interference during fetal procedures.

Purpose of the Study:

  • To evaluate the impact of modified needle designs on fetal blood sampling, transfusion efficiency, and electrocardiography (ECG).
  • Investigate the role of needle bore size, siliconization, and Teflon coating in improving fetal procedures.

Main Methods:

  • Needles were modified with increased internal diameter and siliconization or external Teflon coating.
  • Flow experiments using blood/saline and clinical assessments during fetal transfusion/sampling were conducted.
  • Teflon-coated needles were specifically tested for fetal ECG facilitation during transfusion.

Related Experiment Videos

Main Results:

  • Siliconized needles increased flow rate by 93% and significantly reduced clots in post-transfusion samples.
  • Siliconized needles prevented platelet clumping and clots during fetal platelet count sampling.
  • Teflon-coated needles successfully enabled direct fetal ECG recordings via the intrahepatic vein.

Conclusions:

  • Needle modifications enhance blood flow and minimize coagulation activation in fetal procedures.
  • Siliconization improves sample quality for transfusion and platelet counts.
  • Teflon coating facilitates direct fetal ECG recording by reducing electrical interference.