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Effect of procainamide on platelet adhesion in rats
1Department of Physics, First Military Medical University, Guangzhou, China.
Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica
|July 1, 1994
Abstract:
Effect of procainamide on platelet adhesion in rats was studied with the improved rotating glass sphere method. Procainamide of 136.0, 34.0, 8.5 mumol.L-1 in vitro and 10 mg.kg-1 in vivo inhibited significantly the platelet adhesion with the inhibitory rates of 56%, 28%, 8%, and 24%, respectively. It showed that procainamide given in vitro or in vivo produced an inhibition on platelet adhesion.