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Excretion of 3-hydroxy-diflunisal as a monosulphate conjugate--identification using ESI-MS
R G Dickinson1, A R King, M A Kelly
1Department of Medicine, University of Queensland, Royal Brisbane Hospital, Australia.
Journal of Pharmaceutical and Biomedical Analysis
|September 1, 1994
Abstract:
Electrospray-ionization mass spectrometry was used to identify a novel, highly polar metabolite of diflunisal isolated from Gunn rat urine. Negative ion spectra were obtained of the sulphate conjugate of diflunisal and the new metabolite, which was identified as a sulphate conjugate of 3-hydroxydiflunisal.