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Updated: Aug 9, 2026

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Adaptive response to ionizing radiation in normal and aneuploid human lymphocytes
I Kalina1, H Konecná, G Némethová
1Department of Medical Biology, Medical Faculty, Safarik University, Kosice.
Abstract:
The ability to induce an adaptive response by low doses of gamma rays was studied in normal and trisomic lymphocytes (47, XX or XY, +21). The results indicate the presence of an adaptive response in lymphocytes of 3 normal donors, but in lymphocytes of 5 donors with trisomy 21 no significant adaptive response after irradiation with a low dose of gamma rays was found. There was similar chromosomal radiosensitivity in normal and trisomic lymphocytes (47, XX or XY, +21) irradiated with 1.50 Gy at the 48th hour after stimulation.
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