[Inorganic element analysis on different compatibility of sini decoction]

Area of Science:

• Traditional Chinese Medicine
• Analytical Chemistry
• Pharmacognosy

Background:

• Sini decoction is a widely used traditional Chinese medicine formula.
• Understanding its inorganic element composition is crucial for quality control.
• Variations in herbal components may affect elemental content and extraction.

Purpose of the Study:

• To investigate the impact of different compatibilities and quantities of herbs on inorganic element content in Sini decoction.
• To analyze the extraction rates of these elements under varying prescription conditions.

Main Methods:

• Atomic absorption spectrophotometry (AAS) was employed for elemental analysis.
• Thirteen inorganic elements were quantified in Sini decoction samples.
• Prescriptions were systematically varied in terms of herb type and quantity.

Main Results:

• The quantity and types of herbs used did not significantly alter the concentration of the thirteen analyzed inorganic elements.
• A notable decrease in the extraction rate of inorganic elements was observed as the quantity and number of herbs in the prescription increased.
• Elemental stability suggests robustness, while reduced extraction highlights potential optimization needs.

Conclusions:

• The elemental profile of Sini decoction remains relatively consistent despite variations in herbal composition.
• Increased herbal load negatively impacts the extraction efficiency of inorganic elements.
• Further research should focus on optimizing extraction methods to maximize elemental yield in Sini decoction.