[Antiphospholipid antibodies in women with reproductive disorders]

The authors examined in serum of 121 women, using the ELISA method, anticardiolipine antibodies (ACA) class IgG and IgM. The examined women were divided into a group of women with a normal pregnancy (n = 14), a group of women with imminent abortion during the first trimester (n = 10) and a group of women treated for prolonged periods on account of sterility (n = 97). In women with a normal pregnancy only in one a positive titre in the IgG class was recorded. In the group with imminent abortion a positive ACA titre was found in three patients (30%); in women with negative results of the ACA examination, pregnancy continued. In sterile women positive ACA tests were recorded in 14.5%.