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Hypoglycemic effects of leucodelphinidin derivative isolated from Ficus bengalensis (Linn)
B S Geetha1, B C Mathew, K T Augusti
1Department of Biochemistry, University of Kerala, Trivandrum.
Indian Journal of Physiology and Pharmacology
|July 1, 1994
Abstract:
A Leucodelphinidin derivative isolated from the bark of Ficus bengalensis Linn demonstrated hypoglycemic action at a dosage of 250 mg/kg given both in normal and alloxan diabetic rats. It's action is closely similar to that of an effective dose of glibenclamide (2 mg/kg) tested under the same conditions. However, after a glucose load the plant product is only just significantly active but not as effective as the sulphonylurea. The efficacy of the plant product as a hydroglycemic agent adds to its other therapeutic effects, as it belongs to the class of flavonoids.