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Dermatologic manifestations of antimicrobial adverse reactions with special emphasis on topical exposure
1Ochsner Medical Institutions, New Orleans, Louisiana.
Infectious Disease Clinics of North America
|September 1, 1994
Abstract:
Topical application of antimicrobial agents can lead to an increased risk of systemic reactions. Adverse reactions can occur with topical antifungals and antiviral agents in addition to antibiotics.
Insights
Topical antimicrobial agents, including antifungals and antivirals, can cause systemic adverse reactions. This highlights the importance of monitoring patients for unexpected side effects from these treatments.
Area of Science:
- Dermatology
- Pharmacology
- Infectious Diseases
Background:
- Topical antimicrobial agents are widely used for various infections.
- Systemic absorption of topical medications can occur.
- Adverse reactions are a known risk with topical treatments.
Purpose of the Study:
- To review the potential for systemic reactions from topical antimicrobial agents.
- To highlight adverse events associated with topical antifungals, antivirals, and antibiotics.
Main Methods:
- Literature review of adverse event reports.
- Analysis of systemic reactions linked to topical antimicrobial use.
Main Results:
- Topical antibiotics, antifungals, and antivirals have been associated with systemic adverse reactions.
- These reactions can range in severity and presentation.
Conclusions:
- Clinicians should be aware of the risk of systemic reactions with topical antimicrobials.
- Vigilant monitoring for adverse events is crucial in patients using these agents.