Catabolite repression of cellulase biosynthesis in Streptomyces albaduncus

The cellulase complex of S. albaduncus was found to undergo catabolite repression in the presence of glycerol accompanied by a decrease in the pH of the medium. The results of the experiments conducted at two different initial pH of the medium suggested that pH effect as well as proteases were involved in the inactivation of glucanases (exoglucanase and endoglucanase) whereas beta-glucosidase inactivation was solely due to 'pH effect'. It was also apparent that pH change followed by the addition of glycerol caused alterations in protease activities as well as pattern of their production.