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Updated: Aug 5, 2026

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
Published on: March 14, 2017
Hypercalcemia. How to pinpoint the cause and customize treatment
1Section of Endocrinology and Metabolism, Lahey Clinic Medical Center, Burlington, Massachusetts.
Abstract:
Hypercalcemia is a commonly diagnosed metabolic disorder that is most often caused by primary hyperparathyroidism or malignant disease. Parathyroid hormone assays are useful and reliable in differential diagnosis. Treatment depends on the degree of hypercalcemia, symptoms, and the underlying cause. Pharmacologic therapy, especially with bisphosphonates, may effectively lower serum calcium levels, but the underlying cause of the hypercalcemia must be treated to definitively restored normocalcemia.
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