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Related Experiment Videos

Recurrent corneal erosion: clinical features

M W Hope-Ross1, P B Chell, G N Kervick

  • 1Birmingham and Midland Eye Hospital, UK.

Eye (London, England)
|January 1, 1994
PubMed
Summary

Recalcitrant recurrent corneal erosions are strongly linked to meibomian gland dysfunction. This condition affects tear film stability and presents with superficial corneal and facial abnormalities.

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Area of Science:

  • Ophthalmology
  • Dermatology

Background:

  • Recurrent corneal erosions (RCE) can be challenging to treat.
  • Meibomian gland dysfunction (MGD) is a common ocular surface disease.

Purpose of the Study:

  • To evaluate clinical features of patients with recalcitrant RCE.
  • To investigate potential associations between RCE and ocular/facial abnormalities.

Main Methods:

  • Clinical evaluation of 30 patients with recalcitrant RCE.
  • Documentation of ocular and facial abnormalities.
  • Assessment of meibomian gland structure and tear film parameters.

Main Results:

  • All patients exhibited MGD, characterized by gland dropout and inspissation.
  • Reduced tear film break-up time was universal.
  • Superficial corneal abnormalities (maps, dots, fingerprints) were seen in 93% of patients.
  • Facial abnormalities (telangiectasia, rhinophyma, acne rosacea) were present in 73%.

Conclusions:

  • A significant association exists between recalcitrant RCE and MGD.
  • MGD may play a crucial role in the pathogenesis of severe RCE.
  • Comprehensive evaluation including ocular surface and facial features is warranted.

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