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Updated: Aug 14, 2026

The Forced Swim Test as a Model of Depressive-like Behavior
Published on: March 2, 2015
Neuroendocrine tests in depressive stroke patients
H Dam1, H E Pedersen, H Dige-Petersen
1Psychiatric Department, Rigshospitalet, Copemhagen, Denmark.
Abstract:
1. In the present study 63 stroke patients and 23 control patients participated. The presence and degree of depression was defined by the Hamilton Rating Scale for Depression and the Research Diagnostic Criteria. 2. The TRH stimulation test was performed in all the patients. 3. No difference in Delta Max TSH was found between stroke patients and control patients. 4. No difference in Delta Max TSH was found between patients with the lesion in the right or left hemisphere. 5. No correlation was found between the frequency of blunted response to the TRH stimulation test and the presence of depression. 6. No difference in Delta Max TSH was found between suppressors and non-suppressors to the DST.

