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Updated: Aug 14, 2026

Isolation of Cerebrospinal Fluid from Rodent Embryos for use with Dissected Cerebral Cortical Explants
Published on: March 11, 2013
[The development of water-electrolyte homeostasis during normal and disordered embryogenesis in rats]
It has been shown that venous congestion both in mother and in foetus affects water and salt content with a tendency to decrease the latter, the effect being more significant in the foetus. Prolonged pregnancy did not affect water and salt metabolism in tissues of adult rats, whereas accumulation of liquid was found in foetuses. Water deprivation did not result in significant changes of water and salt balance in tissues. The role of extraembryonic organs in formation of hydro-ionic balance of the foetus under various conditions of pregnancy was revealed.
It has been shown that venous congestion both in mother and in foetus affects water and salt content with a tendency to decrease the latter, the effect being more significant in the foetus. Prolonged pregnancy did not affect water and salt metabolism in tissues of adult rats, whereas accumulation of liquid was found in foetuses. Water deprivation did not result in significant changes of water and salt balance in tissues. The role of extraembryonic organs in formation of hydro-ionic balance of the foetus under various conditions of pregnancy was revealed.

