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Heat shock protein-peptide complexes in cancer immunotherapy
1Department of Biological Sciences, Fordham University, Bronx, New York 10458.
Current Opinion in Immunology
|October 1, 1994
Abstract:
Heat shock proteins (HSPs) are associated with a broad spectrum of peptides derived from the cells from which they are isolated. Vaccination with such HSP-peptide complexes elicits protective immunity against tumors or other cells used as the source of HSPs. These observations suggest that HSP-peptide complexes are suitable as vaccines against cancers and infectious diseases.