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Pdha-2: a model for studying transcriptional regulation in early spermatocytes
R C Iannello1, J C Young, I Kola
1Molecular Embryology and Birth Defects Laboratory, Monash Medical Centre, Clayton, Victoria, Australia.
Molecular Reproduction and Development
|October 1, 1994
Abstract:
Precise temporal and tissue-specific expression of genes during spermatocyte differentiation is crucial for the formation of functional spermatozoa. However, the mechanisms that regulate gene expression during spermatogenesis are poorly understood. One testis-specific gene, Pdha-2, is beginning to emerge as a potentially important model for the study of these events. This review focuses on our current understanding of the expression and regulation of Pdha-2 during spermatogenesis.