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Related Experiment Videos

Mitral valve prolapse

R B Devereux1

  • 1Department of Medicine, New York Hospital-Cornell Medical Center, New York City.

Journal of the American Medical Women'S Association (1972)
|November 1, 1994
PubMed
Summary
This summary is machine-generated.

Mitral valve prolapse (MVP) is a common inherited heart condition diagnosed via physical exam and echocardiography. Its severity and potential complications depend on the degree of mitral regurgitation, guiding patient follow-up.

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Area of Science:

  • Cardiology
  • Genetics
  • Diagnostic Imaging

Background:

  • Mitral valve prolapse (MVP) is typically an inherited condition.
  • Diagnosis involves auscultation (midsystolic click, late-systolic murmur) and dynamic postural changes.
  • Echocardiography is key for confirming MVP and assessing severity.

Purpose of the Study:

  • To detail the diagnostic methods for mitral valve prolapse.
  • To describe the clinical presentation of the
  • MVP syndrome
  • .
  • To outline the potential complications and risk factors associated with MVP.

Main Methods:

  • Clinical auscultation with postural maneuvers.
  • Echocardiography (M-mode and 2-D) for prolapse and leaflet abnormalities.

Related Experiment Videos

  • Assessment of mitral regurgitation, leaflet/annulus dimensions, and leaflet apposition.

    • Main Results:

    • Echocardiography confirms prolapse, leaflet billowing, and can detect severe MVP with mitral regurgitation, leaflet thickening, and annular enlargement.
    • The "MVP syndrome" includes low body weight/blood pressure, skeletal issues, orthostatic hypotension, palpitations, and variable mitral regurgitation.
    • Complications include progressive regurgitation, endocarditis, neurologic events, sudden death, and syncope.

    Conclusions:

    • MVP patients without murmurs or Doppler evidence of mitral regurgitation have a benign prognosis.
    • Risk factors for MVP complications include older age, male gender, murmur presence, and potentially higher weight/blood pressure.
    • The degree of mitral regurgitation dictates the follow-up frequency and intensity for MVP patients.