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[Late ventricular potentials and mitral valve prolapse]

D Babuty1, J C Charniot, C Delhomme

  • 1Service de cardiologie B, hôpital Trousseau, Tours.

Archives Des Maladies Du Coeur Et Des Vaisseaux
|March 1, 1994
PubMed
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Ventricular late potentials (LP) do not predict complex ventricular arrhythmias in mitral valve prolapse (MVP). However, LPs are associated with a higher incidence of non-sustained ventricular tachycardia (NSVT) in MVP patients.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiac Diagnostics

Background:

  • Mitral valve prolapse (MVP) is a common valvular condition.
  • Ventricular arrhythmias are a potential complication of MVP.
  • Predictive markers for these arrhythmias are clinically significant.

Purpose of the Study:

  • To evaluate the predictive value of ventricular late potentials (LP) for ventricular arrhythmias in patients with mitral valve prolapse (MVP).
  • To assess the relationship between echocardiographic findings in MVP and the occurrence of ventricular arrhythmias.

Main Methods:

  • Signal-averaged ECG (SAECG) and 24-hour Holter monitoring were performed in 68 MVP patients.
  • Patients with bundle branch block or other cardiac diseases were excluded.
  • Echocardiography assessed mitral valve morphology and function.

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Main Results:

  • Eighteen patients (26.5%) had ventricular late potentials (LP).
  • Complex ventricular arrhythmias were more frequent in patients with mitral regurgitation (62.8% vs 27.7%, p < 0.005).
  • Non-sustained ventricular tachycardia (NSVT) incidence was significantly higher in patients with LP (44.4% vs 10%, p < 0.005).

Conclusions:

  • Ventricular late potentials (LP) do not appear to be a significant predictor of complex ventricular arrhythmias in mitral valve prolapse (MVP).
  • LP are associated with an increased incidence of non-sustained ventricular tachycardia (NSVT) in MVP patients.
  • Mitral regurgitation is linked to a higher prevalence of complex ventricular arrhythmias in MVP.