Related Experiment Videos
Fumonisin mycotoxicosis in broilers. Weights and serum chemistry modifications
Y Espada1, R Ruiz de Gopegui, C Cuadradas
1Faculty of Veterinary Science, Universidad Autónoma Barcelona, Bellaterra, Spain.
Avian Diseases
|July 1, 1994
Summary
Fumonisin B1 (FB1) intoxication negatively impacts broiler chickens, causing reduced body weight and altered liver enzymes. Even low doses of FB1 from pure sources or Fusarium moniliforme are toxic to young chicks.
Area of Science:
- Animal Science
- Toxicology
- Poultry Health
Background:
- Fumonisin B1 (FB1) is a mycotoxin produced by Fusarium species.
- Poultry are susceptible to mycotoxin contamination in feed.
- Understanding FB1 toxicity is crucial for poultry production.
Purpose of the Study:
- To evaluate the toxic effects of fumonisin B1 (FB1) on broiler chickens.
- To assess the impact of different FB1 doses and sources on chick health.
- To determine recovery patterns after FB1 exposure.
Main Methods:
- Three experiments involving 2-day-old broiler chicks.
- Dietary administration of pure FB1 (10 mg/kg) or Fusarium moniliforme culture material (30 mg/kg or 300 mg/kg).
- Necropsy at different time points, including a 5-week recovery period; biochemical analysis of blood and tissue parameters.
Main Results:
- Intoxicated chicks showed diarrhea, decreased body weight, and altered absolute/relative organ weights (liver, spleen, bursa).
- Significant changes in blood biochemistry included decreased triglycerides, uric acid, and alkaline phosphatase.
- Increased levels of gamma glutamyl transferase, aspartate aminotransferase, lactic dehydrogenase, creatine kinase, and cholesterol were observed.
Conclusions:
- Low doses of FB1, whether pure or from Fusarium moniliforme, are toxic to young broiler chicks.
- FB1 intoxication causes significant physiological and biochemical disturbances in chickens.
- Further research may be needed to understand long-term effects and recovery.